Acupuncture for Improving Immune System Function Acupuncture is a traditional therapy that may influence certain immune and inflammatory responses in the body. However, there is currently insufficient clinical evidence to conclude that acupuncture reliably strengthens the immune system or prevents infections. It may be considered a complementary therapy for general well-being and symptom management, but it should not replace vaccination, appropriate medical treatment, or other evidence-based preventive measures. How acupuncture may affect immune function Research suggests acupuncture may influence several biological pathways involved in immune regulation: Natural killer cells: Some studies report changes in NK-cell activity, which is involved in the body's defense against infected and abnormal cells. T-cell balance: Research has examined effects on CD4+, CD8+ and regulatory T cells. Inflammatory responses: Acupuncture may affect inflammatory signaling molecules, including interleukins and C-reactive protein. Stress regulation: Acupuncture may influence the nervous system and stress responses, which interact with immune function. These findings are promising but mostly concern biological markers. Changes in immune markers do not necessarily mean fewer infections or better protection against disease.